The biology of neuromodulation
Our lab focuses on understanding on how neuromodulatory clusters in the brain, particularly noradrenergic systems, influence cognitive and motor control of behavior. We are interested in research questions that range from the basic biology of the locus coeruleus norepinephrine system through to noradrenergic dysfunction in different disease states. To answer our questions we use a range of electrophysiological, genetic, anatomical and behavioral techniques in rodent models.
Alcohol, stress and Norepinephrine aka Making it hard to think clearly
Locus coeruleus, premotor cortex and behavioral execution aka Brain says OK Go!
Currently funded by NIMH
Our overarching goals are to characterize the neural and physiological mechanisms that integrate cognitive and motor output and apply this information to identifying treatments for circuit dysfunction in disease.